close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3812Conserved protein of unknown function, TPR-like; Homologs of previously reported genes of unknown function; 14659697, 15361863, 16893176, 7667876, 9482716. (723 aa)    
Predicted Functional Partners:
NIDE3811
Homologs of previously reported genes of unknown function.
 
     0.903
NIDE0948
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 11777911, 14659697, 15223324, 1882418, 7667876, 9482716.
 
     0.758
NIDE2403
Homologs of previously reported genes of unknown function.
 
     0.757
ruvB
Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.733
NIDE2408
Putative Lipopolysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.729
NIDE3274
Protein of unknown function, contains TPR repeats; No homology to any previously reported sequences; 16893176, 7667876, 9482716.
 
     0.723
NIDE1061
Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function.
  
     0.656
NIDE3810
Conserved protein of unknown function, contains Ankyrin repeats; Homologs of previously reported genes of unknown function; 8108379.
       0.654
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.624
NIDE3813
Exported protein of unknown function; No homology to any previously reported sequences; 16339899, 2539596, 7519681.
       0.623
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: medium (46%) [HD]