| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE1720 | higB | NIDE1720 | NIDE3841 | Putative Antidote of proteic killer gene system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | 0.844 |
| NIDE2142 | higB | NIDE2142 | NIDE3841 | Putative Antidote of proteic killer gene system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | 0.846 |
| NIDE3840 | higA | NIDE3840 | NIDE3842 | Protein of unknown function; No homology to any previously reported sequences. | Antitoxin of plasmid maintenance system; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. | 0.420 |
| NIDE3840 | higB | NIDE3840 | NIDE3841 | Protein of unknown function; No homology to any previously reported sequences. | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | 0.437 |
| NIDE3843 | higA | NIDE3843 | NIDE3842 | Protein of unknown function; No homology to any previously reported sequences. | Antitoxin of plasmid maintenance system; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. | 0.645 |
| NIDE3843 | higB | NIDE3843 | NIDE3841 | Protein of unknown function; No homology to any previously reported sequences. | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | 0.616 |
| higA | NIDE3840 | NIDE3842 | NIDE3840 | Antitoxin of plasmid maintenance system; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. | Protein of unknown function; No homology to any previously reported sequences. | 0.420 |
| higA | NIDE3843 | NIDE3842 | NIDE3843 | Antitoxin of plasmid maintenance system; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. | Protein of unknown function; No homology to any previously reported sequences. | 0.645 |
| higA | higB | NIDE3842 | NIDE3841 | Antitoxin of plasmid maintenance system; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | 0.968 |
| higB | NIDE1720 | NIDE3841 | NIDE1720 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Putative Antidote of proteic killer gene system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. | 0.844 |
| higB | NIDE2142 | NIDE3841 | NIDE2142 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Putative Antidote of proteic killer gene system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. | 0.846 |
| higB | NIDE3840 | NIDE3841 | NIDE3840 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Protein of unknown function; No homology to any previously reported sequences. | 0.437 |
| higB | NIDE3843 | NIDE3841 | NIDE3843 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Protein of unknown function; No homology to any previously reported sequences. | 0.616 |
| higB | higA | NIDE3841 | NIDE3842 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Antitoxin of plasmid maintenance system; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. | 0.968 |
| higB | mazF | NIDE3841 | NIDE2509 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Toxin MazF; Toxic component of a type II toxin-antitoxin (TA) system. | 0.756 |
| higB | stbE | NIDE3841 | NIDE4297 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Addiction module toxin; Function of strongly homologous gene; cell process. | 0.804 |
| higB | yefM | NIDE3841 | NIDE1373 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Antitoxin of toxin-antitoxin stability system; Antitoxin component of a type II toxin-antitoxin (TA) system. | 0.764 |
| higB | yefM-2 | NIDE3841 | NIDE2383 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Addiction module antitoxin yefM; Antitoxin component of a type II toxin-antitoxin (TA) system. | 0.764 |
| higB | yoeB | NIDE3841 | NIDE2382 | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | Addiction module toxin YoeB; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.809 |
| mazF | higB | NIDE2509 | NIDE3841 | Toxin MazF; Toxic component of a type II toxin-antitoxin (TA) system. | Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin. | 0.756 |