Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3855Putative Acyl carrier protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (85 aa)    
Predicted Functional Partners:
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.985
NIDE3854
Putative Pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase (E2) component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.945
fabD
Malonyl-CoA-(acyl-carrier-protein) transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.887
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.857
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 0.846
rplJL
Fused 50S ribosomal proteins L10 and L7/L12 (modular protein); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
 0.824
acsA-2
Acetyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.823
fabI
Enoyl-[acyl-carrier-protein] reductase (NADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.802
NIDE3856
Homologs of previously reported genes of unknown function.
 
     0.801
rplQ
50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.
   
 0.783
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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