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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3880Conserved protein of unknown function, putative Polyphosphate kinase; Homologs of previously reported genes of unknown function; 12486232. (327 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.944
ppa
Inorganic pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.914
NIDE3879
Putative Cytochrome c (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
    0.782
trxC
Thioredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier.
       0.668
NIDE3621
Exported protein of unknown function, putative Outer membrane protein; No homology to any previously reported sequences.
   
    0.661
NIDE3881
Conserved protein of unknown function, DsrE-like; Homologs of previously reported genes of unknown function; 9695921.
       0.621
NIDE3647
Exported protein of unknown function; No homology to any previously reported sequences.
   
    0.532
qcrB
Quinol-cytochrome c reductase, fused cytochrome b/c subunit; Function of strongly homologous gene; carrier.
  
  
 0.503
NIDE1853
Putative Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.471
NIDE2415
Putative Exopolyphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.441
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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