Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nhaPNa+/H+ antiporter; Function of strongly homologous gene; transporter. (410 aa)    
Predicted Functional Partners:
nuoL
NADH-quinone oxidoreductase, membrane subunit L; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.751
NIDE3946
Protein of unknown function; No homology to any previously reported sequences.
       0.737
nuoL-2
NADH-quinone oxidoreductase, membrane subunit L; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.718
chaA
Calcium/proton antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 
 
 0.648
mrp
Putative ATPase, Mrp homolog; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
      
 0.632
mrp-2
Protein Mrp, putative ATPase (fragment); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
      
 0.632
pdaD
Arginine decarboxylase, pyruvoyl-dependent; Function of strongly homologous gene; enzyme.
      
 0.622
NIDE4168
Putative Glutathione-regulated potassium-efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
 
 0.575
NIDE3947
Putative Small-conductance mechanosensitive channel MscS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.436
nuoN
NADH-quinone oxidoreductase, membrane subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
      
 0.424
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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