| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE0405 | NIDE3957 | NIDE0405 | NIDE3957 | Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences; 11183780, 11532124, 1619650, 1986310, 9738943. | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.841 |
| NIDE3955 | NIDE3957 | NIDE3955 | NIDE3957 | Protein of unknown function; No homology to any previously reported sequences. | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.525 |
| NIDE3955 | NIDE3958 | NIDE3955 | NIDE3958 | Protein of unknown function; No homology to any previously reported sequences. | Homologs of previously reported genes of unknown function. | 0.522 |
| NIDE3955 | maf | NIDE3955 | NIDE3956 | Protein of unknown function; No homology to any previously reported sequences. | Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.525 |
| NIDE3957 | NIDE0405 | NIDE3957 | NIDE0405 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Protein of unknown function, putative transcriptional regulator; No homology to any previously reported sequences; 11183780, 11532124, 1619650, 1986310, 9738943. | 0.841 |
| NIDE3957 | NIDE3955 | NIDE3957 | NIDE3955 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Protein of unknown function; No homology to any previously reported sequences. | 0.525 |
| NIDE3957 | NIDE3958 | NIDE3957 | NIDE3958 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Homologs of previously reported genes of unknown function. | 0.826 |
| NIDE3957 | NIDE3959 | NIDE3957 | NIDE3959 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Protein of unknown function, contains CBS domain pair; No homology to any previously reported sequences; 15326606, 9020585. | 0.529 |
| NIDE3957 | guaA | NIDE3957 | NIDE1422 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.498 |
| NIDE3957 | guaB | NIDE3957 | NIDE1421 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.504 |
| NIDE3957 | maf | NIDE3957 | NIDE3956 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.891 |
| NIDE3957 | panC | NIDE3957 | NIDE0501 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.706 |
| NIDE3957 | proS | NIDE3957 | NIDE1509 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.695 |
| NIDE3957 | rsmB | NIDE3957 | NIDE0396 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.593 |
| NIDE3958 | NIDE3955 | NIDE3958 | NIDE3955 | Homologs of previously reported genes of unknown function. | Protein of unknown function; No homology to any previously reported sequences. | 0.522 |
| NIDE3958 | NIDE3957 | NIDE3958 | NIDE3957 | Homologs of previously reported genes of unknown function. | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.826 |
| NIDE3958 | NIDE3959 | NIDE3958 | NIDE3959 | Homologs of previously reported genes of unknown function. | Protein of unknown function, contains CBS domain pair; No homology to any previously reported sequences; 15326606, 9020585. | 0.535 |
| NIDE3958 | maf | NIDE3958 | NIDE3956 | Homologs of previously reported genes of unknown function. | Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.826 |
| NIDE3959 | NIDE3957 | NIDE3959 | NIDE3957 | Protein of unknown function, contains CBS domain pair; No homology to any previously reported sequences; 15326606, 9020585. | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.529 |
| NIDE3959 | NIDE3958 | NIDE3959 | NIDE3958 | Protein of unknown function, contains CBS domain pair; No homology to any previously reported sequences; 15326606, 9020585. | Homologs of previously reported genes of unknown function. | 0.535 |
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