close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE3958Homologs of previously reported genes of unknown function. (502 aa)    
Predicted Functional Partners:
maf
Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.826
NIDE3957
Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.826
NIDE1528
Conserved protein of unknown function, contains FHA domain; Homologs of previously reported genes of unknown function; 11106755, 11911881, 12564991, 7482699.
   
    0.633
NIDE2024
Protein of unknown function, contains FHA and Transglycosylase SLT domain; No homology to any previously reported sequences; 10518219, 10843862, 11106755, 11911881, 12564991, 14625683, 7482699, 8203016.
   
    0.633
NIDE0008
Conserved membrane protein of unknown function, DoxX family; Homologs of previously reported genes of unknown function.
  
  
 0.621
NIDE0036
Conserved membrane protein of unknown function, DoxX family; Homologs of previously reported genes of unknown function.
  
  
 0.621
NIDE3745
Cation-transporting ATPase; Function of strongly homologous gene; transporter.
   
    0.543
mgtA
Magnesium-transporting ATPase, P-type; Function of homologous gene experimentally demonstrated in an other organism; transporter.
   
    0.543
NIDE3786
Putative Calcium-transporting ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
    0.543
NIDE3959
Protein of unknown function, contains CBS domain pair; No homology to any previously reported sequences; 15326606, 9020585.
       0.535
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.