Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdaDArginine decarboxylase, pyruvoyl-dependent; Function of strongly homologous gene; enzyme. (191 aa)    
Predicted Functional Partners:
speB
Agmatinase; Function of strongly homologous gene; enzyme; Belongs to the arginase family.
 
  
 0.928
NIDE0529
Putative Dimethylargininase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
argH
Argininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.800
NIDE3977
Putative Deoxyhypusine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.748
nhaP
Na+/H+ antiporter; Function of strongly homologous gene; transporter.
      
 0.622
gapD
Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
       0.544
NIDE3971
Putative Pseudouridine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the pseudouridine synthase RsuA family.
       0.489
NIDE3975
Protein of unknown function; No homology to any previously reported sequences.
       0.457
pepP
Xaa-Pro aminopeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase M24B family.
      
 0.426
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (22%) [HD]