| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE1439 | gapD | NIDE1439 | NIDE3974 | Conserved protein of unknown function, contains GH3 auxin responsive-like domain; Homologs of previously reported genes of unknown function. | Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. | 0.747 |
| NIDE3103 | acsA | NIDE3103 | NIDE1643 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.712 |
| NIDE3103 | atoB | NIDE3103 | NIDE3116 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
| NIDE3103 | fadA | NIDE3103 | NIDE3104 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
| NIDE3103 | gapD | NIDE3103 | NIDE3974 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. | 0.839 |
| NIDE3103 | mdh | NIDE3103 | NIDE3562 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.785 |
| NIDE3103 | paaF | NIDE3103 | NIDE3102 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.999 |
| NIDE3103 | pccB | NIDE3103 | NIDE3121 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Propionyl-CoA carboxylase; Function of strongly homologous gene; enzyme. | 0.985 |
| NIDE3975 | gapD | NIDE3975 | NIDE3974 | Protein of unknown function; No homology to any previously reported sequences. | Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. | 0.746 |
| acsA | NIDE3103 | NIDE1643 | NIDE3103 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.712 |
| acsA | atoB | NIDE1643 | NIDE3116 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.981 |
| acsA | fadA | NIDE1643 | NIDE3104 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.973 |
| acsA | gapD | NIDE1643 | NIDE3974 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. | 0.692 |
| acsA | mdh | NIDE1643 | NIDE3562 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.726 |
| acsA | paaF | NIDE1643 | NIDE3102 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.872 |
| acsA | pccB | NIDE1643 | NIDE3121 | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Propionyl-CoA carboxylase; Function of strongly homologous gene; enzyme. | 0.567 |
| atoB | NIDE3103 | NIDE3116 | NIDE3103 | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.999 |
| atoB | acsA | NIDE3116 | NIDE1643 | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.981 |
| atoB | fadA | NIDE3116 | NIDE3104 | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | 0.944 |
| atoB | gapD | NIDE3116 | NIDE3974 | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. | Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. | 0.765 |
