Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE3977Putative Deoxyhypusine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (367 aa)    
Predicted Functional Partners:
efp
Elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
   
 0.871
NIDE3976
Exported protein of unknown function, putative DsbA-like oxidoreductase; No homology to any previously reported sequences; 2181145, 2668278, 3371540, 3896121, 7635143, 7788289, 7788290, 7940678, 9149147, 9655827.
       0.820
pdaD
Arginine decarboxylase, pyruvoyl-dependent; Function of strongly homologous gene; enzyme.
 
   
 0.748
speB
Agmatinase; Function of strongly homologous gene; enzyme; Belongs to the arginase family.
 
   
 0.666
NIDE3975
Protein of unknown function; No homology to any previously reported sequences.
       0.610
gapD
Succinate semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
       0.539
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.538
NIDE1703
Homologs of previously reported genes of unknown function.
  
     0.436
NIDE3978
Putative Divalent metal cation permease, ZupT-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.433
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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