Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrcAPenicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (797 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Function of strongly homologous gene; enzyme.
  
 
0.955
ftsI
Peptidoglycan glycosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
0.950
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
0.939
NIDE3591
Putative Penicillin-binding protein 1B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 
0.919
NIDE0434
Putative D-alanyl-D-alanine carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S11 family.
     
 0.914
NIDE0773
Putative Esterase, beta-lactamase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.912
ftsW
Cell division protein FtsW; Function of homologous gene experimentally demonstrated in an other organism; cell process; Belongs to the SEDS family.
  
   
 0.845
ddlB
D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
  
 0.771
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
   
 0.756
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
   
 0.719
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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