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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4061Protein of unknown function; No homology to any previously reported sequences. (190 aa)    
Predicted Functional Partners:
scpAa
Methylmalonyl-CoA mutase (N-terminal fragment); Function of strongly homologous gene; enzyme.
    
 0.915
scpAb
Methylmalonyl-CoA mutase (C-terminal fragment); Function of strongly homologous gene; enzyme.
    
 0.915
NIDE3109
Putative 4-hydroxyphenylpyruvate dioxygenase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.907
NIDE3844
Protein of unknown function; No homology to any previously reported sequences.
    
 0.907
NIDE4062
Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
  
  
 0.794
NIDE4063
Conserved protein of unknown function, putative Saccharopine dehydrogenase; Homologs of previously reported genes of unknown function.
  
  
 0.787
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
  
 0.514
NIDE4064
Conserved protein of unknown function, contains PSP1-like region; Homologs of previously reported genes of unknown function.
  
    0.506
nuoI
NADH-quinone oxidoreductase, subunit I (modular protein); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  
 0.487
nuoI-2
NADH-quinone oxidoreductase, subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  
 0.487
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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