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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4062Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (518 aa)    
Predicted Functional Partners:
NIDE4063
Conserved protein of unknown function, putative Saccharopine dehydrogenase; Homologs of previously reported genes of unknown function.
 
  
 0.956
acsA
Acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.949
acsA-2
Acetyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.949
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.929
NIDE1138
Putative 3-hydroxyisobutyrate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.922
garR
2-hydroxy-3-oxopropionate reductase; Function of strongly homologous gene; enzyme.
 
 
 0.922
NIDE4352
3-hydroxyacid dehydrogenase; Function of strongly homologous gene; enzyme.
  
 
 0.922
adhC
Alcohol dehydrogenase, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.918
NIDE3103
Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.917
acyP
Acylphosphatase; Function of strongly homologous gene; enzyme.
    
 0.912
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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