NIDE4076 protein (Nitrospira defluvii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NIDE4076

Protein of unknown function; No homology to any previously reported sequences. (494 aa)

Predicted Functional Partners:

nuoCD

0.928

nuoD

0.730

nuoB

0.670

nuoB-2

0.670

nuoC

0.667

NIDE1238

0.648

crtB

0.648

nuoI

0.642

nuoI-2

0.642

yfhL

0.642

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE1238	NIDE4076	NIDE1238	NIDE4076	Squalene synthase; Function of strongly homologous gene; enzyme.	Protein of unknown function; No homology to any previously reported sequences.	0.648
NIDE1238	nuoB	NIDE1238	NIDE0235	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.630
NIDE1238	nuoB-2	NIDE1238	NIDE0614	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.630
NIDE1238	nuoC	NIDE1238	NIDE0234	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.	0.686
NIDE1238	nuoCD	NIDE1238	NIDE0613	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.	0.899
NIDE1238	nuoD	NIDE1238	NIDE0233	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.	0.645
NIDE1238	nuoI	NIDE1238	NIDE0231	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunit I (modular protein); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.494
NIDE1238	nuoI-2	NIDE1238	NIDE0607	Squalene synthase; Function of strongly homologous gene; enzyme.	NADH-quinone oxidoreductase, subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.494
NIDE1238	yfhL	NIDE1238	NIDE4140	Squalene synthase; Function of strongly homologous gene; enzyme.	4Fe-4S ferredoxin; Function of strongly homologous gene; carrier.	0.494
NIDE4076	NIDE1238	NIDE4076	NIDE1238	Protein of unknown function; No homology to any previously reported sequences.	Squalene synthase; Function of strongly homologous gene; enzyme.	0.648
NIDE4076	crtB	NIDE4076	NIDE1520	Protein of unknown function; No homology to any previously reported sequences.	Phytoene synthase; Function of strongly homologous gene; enzyme.	0.648
NIDE4076	nuoB	NIDE4076	NIDE0235	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.670
NIDE4076	nuoB-2	NIDE4076	NIDE0614	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.670
NIDE4076	nuoC	NIDE4076	NIDE0234	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.	0.667
NIDE4076	nuoCD	NIDE4076	NIDE0613	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.	0.928
NIDE4076	nuoD	NIDE4076	NIDE0233	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.	0.730
NIDE4076	nuoI	NIDE4076	NIDE0231	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunit I (modular protein); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.642
NIDE4076	nuoI-2	NIDE4076	NIDE0607	Protein of unknown function; No homology to any previously reported sequences.	NADH-quinone oxidoreductase, subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.642
NIDE4076	yfhL	NIDE4076	NIDE4140	Protein of unknown function; No homology to any previously reported sequences.	4Fe-4S ferredoxin; Function of strongly homologous gene; carrier.	0.642
crtB	NIDE4076	NIDE1520	NIDE4076	Phytoene synthase; Function of strongly homologous gene; enzyme.	Protein of unknown function; No homology to any previously reported sequences.	0.648