STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE4085Putative Peptidase M; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (729 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.983
NIDE4084
Putative Protein TolB (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.862
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.852
NIDE0346
Exported protein of unknown function, DUF399; No homology to any previously reported sequences.
     0.844
cysK
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.815
NIDE4083
Membrane protein of unknown function, putative Phosphoesterase; No homology to any previously reported sequences; 17079146, 9041652, 9260289.
       0.802
aspC
Aspartate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.801
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response).
  
  
 0.776
NIDE4086
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.737
NIDE3190
Putative Peptidase, M28 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.645
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.