close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilDType IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (259 aa)    
Predicted Functional Partners:
gspE2
General secretion pathway protein E, contains GAF domain; Function of strongly homologous gene; transporter.
 
 
 0.942
gspE
General secretion pathway protein E; Function of strongly homologous gene; transporter.
 
 
 0.942
pilC
Type IV pilus biogenesis protein PilC; Function of strongly homologous gene; transporter.
 
  
 0.891
gspF
General secretion pathway protein F; Function of strongly homologous gene; transporter.
 
  
 0.890
NIDE4097
Putative Type IV pilus assembly protein PilB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
 
 0.889
pilM
Type IV pilus biogenesis protein PilM; Function of strongly homologous gene; structure.
 
  
 0.849
pilT1
Twitching mobility protein PilT; Function of homologous gene experimentally demonstrated in an other organism; structure.
 
   
 0.829
NIDE2734
Putative Competence protein ComEC/Rec2 related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.821
pilT2
Twitching mobility protein PilT; Function of homologous gene experimentally demonstrated in an other organism; structure.
  
   
 0.800
smf
Protein SMF, putative DNA protecting protein DprA; Function of strongly homologous gene; phenotype.
  
  
 0.783
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.