Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
NIDE4156Protein of unknown function, contains Diguanylate kinase domain; No homology to any previously reported sequences; 11682196, 15063857, 15306016, 15569936, 15716451. (583 aa)    
Predicted Functional Partners:
NIDE0815
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.777
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.775
NIDE1870
Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator.
 
  
 0.762
NIDE2310
Protein of unknown function, contains Diguanylate cyclase domain; No homology to any previously reported sequences; 11682196, 15063857, 15075296, 15306016, 15569936, 15716451, 16418169, 17010156, 7592388.
  
     0.762
NIDE2323
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.759
NIDE1024
Protein of unknown function, putative HD-type Metal-dependent phosphohydrolase; No homology to any previously reported sequences.
  
 
 0.756
NIDE2649
Protein of unknown function, contains HD and HPt domains; No homology to any previously reported sequences; 11148031, 11489844, 11934609, 15476819, 9868367.
  
 
 0.756
NIDE1046
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.755
NIDE0687
Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator.
 
  
 0.748
NIDE0257
Protein of unknown function; No homology to any previously reported sequences.
    
 
 0.734
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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