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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
engAGTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (464 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.983
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.947
rluB
23S rRNA pseudouridylate synthase B (modular protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.843
NIDE2595
Pseudouridine synthase, rsuA family; Function of strongly homologous gene; enzyme; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.822
typA
GTP-binding protein TypA; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
  
 0.798
NIDE0087
Putative DNA primase, P4 family (phage related); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.770
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
   
  
 0.770
ftsY
Cell division protein ftsY homolog; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.742
NIDE3971
Putative Pseudouridine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.737
scpB
Segregation and condensation protein B (modular protein); Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.698
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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