Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nirKCopper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (321 aa)    
Predicted Functional Partners:
nirA
Ferredoxin-nitrite reductase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.980
narK
Nitrate transporter; Function of strongly homologous gene; transporter.
    
 0.976
nxrA2
Putative Nitrate oxidoreductase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.974
nxrA1
Putative Nitrate oxidoreductase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.964
nxrB1
Putative Nitrate oxidoreductase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.918
NIDE3489
Homologs of previously reported genes of unknown function.
     0.916
NIDE3339
Putative Cytochrome c-type protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
     
 0.908
NIDE2534
Putative Copper-containing nitrite reductase (NO-forming); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 
0.902
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
      
 0.810
amtB
Ammonium transporter Amt; Function of homologous gene experimentally demonstrated in an other organism; transporter.
    
 
 0.766
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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