Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE4254Putative Peptidase M20; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (454 aa)    
Predicted Functional Partners:
NIDE4256
Exported protein of unknown function; No homology to any previously reported sequences.
       0.628
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
 
 0.569
argG
Argininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.565
garR
2-hydroxy-3-oxopropionate reductase; Function of strongly homologous gene; enzyme.
  
    0.553
NIDE4258
Exported protein of unknown function; No homology to any previously reported sequences.
       0.532
glmS
Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 
 0.527
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.511
msrB
Methionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
    
 0.499
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.482
fliG
Flagellar motor switch protein FliG; Function of homologous gene experimentally demonstrated in an other organism; structure.
   
   0.479
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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