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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4261Putative Formate hydrogenlyase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (530 aa)    
Predicted Functional Partners:
NIDE4260
Putative Formate hydrogenlyase, small subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.999
hyfF
Formate hydrogenlyase, membrane subunit; Function of strongly homologous gene; membrane component.
 
 0.999
NIDE4264
Putative Formate hydrogenlyase, membrane subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
 
 0.999
hyfB
Formate hydrogenlyase, membrane subunit; Function of strongly homologous gene; membrane component.
 
 0.999
NIDE4263
Putative Formate hydrogenlyase, membrane subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
  
 0.998
nuoI
NADH-quinone oxidoreductase, subunit I (modular protein); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 0.971
nuoI-2
NADH-quinone oxidoreductase, subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.967
yfhL
4Fe-4S ferredoxin; Function of strongly homologous gene; carrier.
  
 
 0.967
NIDE0232
Putative NADH-quinone oxidoreductase, subunit G; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.958
nuoG
NADH-quinone oxidoreductase, subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
  
 
 0.958
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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