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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyfFFormate hydrogenlyase, membrane subunit; Function of strongly homologous gene; membrane component. (510 aa)    
Predicted Functional Partners:
NIDE4261
Putative Formate hydrogenlyase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.999
NIDE4264
Putative Formate hydrogenlyase, membrane subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
 
 0.993
NIDE4260
Putative Formate hydrogenlyase, small subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.991
NIDE1769
Putative NADH-quinone oxidoreductase, subunit L (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.976
NIDE4263
Putative Formate hydrogenlyase, membrane subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
  
 0.959
NIDE4386
Putative NADH-quinone oxidoreductase, subunit L; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.939
nuoL
NADH-quinone oxidoreductase, membrane subunit L; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.937
nuoL-2
NADH-quinone oxidoreductase, membrane subunit L; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.936
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.898
hyfB
Formate hydrogenlyase, membrane subunit; Function of strongly homologous gene; membrane component.
 
    
0.713
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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