Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybgCAcyl-CoA thioesterase; Function of strongly homologous gene; enzyme. (133 aa)    
Predicted Functional Partners:
NIDE2152
Putative Polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.816
tolQ
Protein TolQ; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.810
tolB
Protein TolB precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.806
tolR
Protein TolR; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.794
lptB
ABC-type transport system, ATPase component, putative lipopolysaccharide transport system; Function of strongly homologous gene; transporter.
      
 0.760
NIDE4309
Conserved protein of unknown function, 23S rRNA-associated protein-like; Homologs of previously reported genes of unknown function; 7751314, 8341711.
       0.678
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.667
NIDE4310
Homologs of previously reported genes of unknown function.
       0.616
glnEb
(Glutamate-ammonia-ligase) adenylyltransferase, subunit B; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the [...]
 
    0.554
fabD
Malonyl-CoA-(acyl-carrier-protein) transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.546
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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