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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4310Homologs of previously reported genes of unknown function. (418 aa)    
Predicted Functional Partners:
ybgC
Acyl-CoA thioesterase; Function of strongly homologous gene; enzyme.
       0.621
NIDE4309
Conserved protein of unknown function, 23S rRNA-associated protein-like; Homologs of previously reported genes of unknown function; 7751314, 8341711.
  
    0.615
NIDE4311
Conserved exported protein of unknown function DUF107; Homologs of previously reported genes of unknown function.
 
     0.585
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.513
qmcA
Putative Protease QmcA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
   0.501
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.455
NIDE1523
Protein of unknown function; No homology to any previously reported sequences; 14731533, 15335710, 1639195, 7531822, 7953536.
   
 0.429
NIDE3282
Exported protein of unknown function, contains WD40 repeats; No homology to any previously reported sequences; 1909108.
   
 0.429
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.422
hscA
Chaperone protein HscA (Hsc66); Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the heat shock protein 70 family.
  
 0.422
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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