STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4311Conserved exported protein of unknown function DUF107; Homologs of previously reported genes of unknown function. (144 aa)    
Predicted Functional Partners:
qmcA
Putative Protease QmcA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.942
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
   
    0.816
NIDE4310
Homologs of previously reported genes of unknown function.
 
     0.584
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
       0.536
NIDE4314
Homologs of previously reported genes of unknown function.
       0.536
hflC
FtsH protease activity modulator HflC; HflC and HflK could regulate a protease.
 
 
 0.526
hflK
FtsH protease activity modulator HflK; HflC and HflK could encode or regulate a protease.
 
 
 0.522
cobJ
Precorrin-3B C(17)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.520
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
   
    0.499
cdsA
Phosphatidate cytidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDS family.
   
    0.481
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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