STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iaaAIsoaspartyl peptidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (312 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.911
aspC
Aspartate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.901
argG
Argininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.900
pyrB
Aspartate carbamoyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
    
  0.900
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
  0.900
lysC
Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
     
 0.806
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
  0.800
NIDE4164
Putative Formimidoyltransferase-cyclodeaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.800
NIDE4326
Homologs of previously reported genes of unknown function.
       0.789
cysNC
Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme.
   
    0.752
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.