STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4331Conserved membrane protein of unknown function DUF477; Homologs of previously reported genes of unknown function. (301 aa)    
Predicted Functional Partners:
NIDE4330
Homologs of previously reported genes of unknown function.
 
     0.957
NIDE4332
Conserved exported protein of unknown function, LemA-like; Homologs of previously reported genes of unknown function.
 
    0.946
NIDE1828
Conserved exported protein of unknown function, DUF477; Homologs of previously reported genes of unknown function.
  
     0.775
NIDE1237
Conserved exported protein of unknown function, Cupredoxin family; Homologs of previously reported genes of unknown function; 1324168, 14673090, 6307356, 7592701, 8083153.
    
   0.727
NIDE0899
Putative Quinol-cytochrome c reductase, cytochrome b subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
    
   0.628
qcrB
Quinol-cytochrome c reductase, fused cytochrome b/c subunit; Function of strongly homologous gene; carrier.
    
   0.628
NIDE3018
Putative L-2-hydroxyglutarate oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
   0.626
mviN-2
Virulence factor MviN homolog; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
       0.620
ogt
Methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.618
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.540
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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