Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4349Homologs of previously reported genes of unknown function. (129 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
       0.762
NIDE2762
Exported protein of unknown function; No homology to any previously reported sequences.
  
     0.676
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.600
NIDE0637
Homologs of previously reported genes of unknown function.
  
     0.517
NIDE0690
Putative TonB-dependent receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
  
     0.452
NIDE2810
Homologs of previously reported genes of unknown function.
  
     0.448
NIDE2107
TonB-dependent receptor, possible Cobalamin transporter; Function of strongly homologous gene; transporter.
  
     0.437
NIDE1252
Homologs of previously reported genes of unknown function.
  
     0.417
NIDE0626
Conserved exported protein of unknown function, contains BNR repeats; Homologs of previously reported genes of unknown function; 2562507.
  
     0.410
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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