STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
NIDE4382Putative Carboxylesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (237 aa)    
Predicted Functional Partners:
NIDE4381
Conserved protein of unknown function, putative Hydrolase; Homologs of previously reported genes of unknown function; 14681380.
     
 0.826
NIDE4380
Protein of unknown function; No homology to any previously reported sequences.
       0.769
NIDE4383
Homologs of previously reported genes of unknown function.
       0.627
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.577
NIDE4187
Putative Peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.565
NIDE4379
Conserved protein of unknown function, contains FMN-binding split barrel; Homologs of previously reported genes of unknown function; 11786019, 12686112, 15858270.
       0.513
ydiU
Conserved protein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
       0.474
NIDE4385
Homologs of previously reported genes of unknown function.
       0.401
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.