Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE4383Homologs of previously reported genes of unknown function. (1074 aa)    
Predicted Functional Partners:
NIDE4381
Conserved protein of unknown function, putative Hydrolase; Homologs of previously reported genes of unknown function; 14681380.
       0.627
NIDE4382
Putative Carboxylesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.627
NIDE4380
Protein of unknown function; No homology to any previously reported sequences.
       0.577
ydiU
Conserved protein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
       0.439
NIDE4385
Homologs of previously reported genes of unknown function.
       0.411
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: medium (50%) [HD]