Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ydiUConserved protein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (491 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.844
nuoG
NADH-quinone oxidoreductase, subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
      0.825
btuE
Predicted Glutathione peroxidase; Function of strongly homologous gene; enzyme; Belongs to the glutathione peroxidase family.
   
  
 0.818
NIDE1493
Putative Sensor histidine kinase with MCP region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      
 0.795
NIDE0425
Putative Acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.780
ppdK
Pyruvate, phosphate dikinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PEP-utilizing enzyme family.
      
 0.733
NIDE4385
Homologs of previously reported genes of unknown function.
       0.725
arsR
Arsenical resistance operon repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.638
lipB
Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
      0.615
btuC
Vitamin B12 import system, permease protein BtuC; Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
      0.477
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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