STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIZ36730.1MobA/MobL protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)    
Predicted Functional Partners:
AIZ36729.1
Replisome organizer; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.856
AIZ36739.1
Recombinase TnpX; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.764
AIZ36732.1
Igma-70 family RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.719
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.698
addA
Helicase; ATP-dependent DNA helicase.
  
 
 0.682
AIZ36003.1
TnpX site-specific recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.672
AIZ36727.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.625
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.573
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.522
AIZ36731.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.452
Your Current Organism:
Parvimonas micra
NCBI taxonomy Id: 33033
Other names: ATCC 33270, CCUG 17638, CCUG 17638 A, CCUG 46357, CIP 105294, DSM 20468, Diplococcus glycinophilus, JCM 12970, KCTC 5196, NCTC 11808, P. micra, Peptococcus glycinophilus, Peptostreptococcus micros, Streptococcus anaerobius micros, Streptococcus micros, VPI 5464, strain 3119B
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