STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIZ37139.1Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.902
AIZ37183.1
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.882
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.878
pyrD
Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.865
pyrF
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.855
AIZ36446.1
Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.804
pyrK
Diguanylate cyclase; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
  
 0.799
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.614
gatA
aspartyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
    0.603
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.594
Your Current Organism:
Parvimonas micra
NCBI taxonomy Id: 33033
Other names: ATCC 33270, CCUG 17638, CCUG 17638 A, CCUG 46357, CIP 105294, DSM 20468, Diplococcus glycinophilus, JCM 12970, KCTC 5196, NCTC 11808, P. micra, Peptococcus glycinophilus, Peptostreptococcus micros, Streptococcus anaerobius micros, Streptococcus micros, VPI 5464, strain 3119B
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