STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ79120.1KEGG: bip:Bint_2080 5.0e-166 acetolactate synthase large subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 9.97. (554 aa)    
Predicted Functional Partners:
KWZ79121.1
Acetolactate synthase, small subunit; KEGG: cls:CXIVA_24100 2.6e-27 hypothetical protein; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 7.50.
 
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.998
ilvD
KEGG: bip:Bint_1862 9.0e-199 livD; dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 7.50; Belongs to the IlvD/Edd family.
 
 0.997
KWZ77680.1
KEGG: apr:Apre_1062 4.5e-197 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 7.50.
  
 0.967
KWZ77698.1
KEGG: apr:Apre_1042 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase.
  
 
 0.954
KWZ79015.1
Putative isocitrate dehydrogenase, NAD-dependent; KEGG: apr:Apre_1101 1.9e-150 isocitrate dehydrogenase K00030; Psort location: Cytoplasmic, score: 9.97.
 0.951
KWZ77679.1
KEGG: apr:Apre_1042 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.951
KWZ75766.1
Trypsin; KEGG: cst:CLOST_2551 5.2e-77 2-alkenal reductase K08070.
     
 0.948
KWZ77998.1
Pyruvate kinase; KEGG: apr:Apre_0677 4.1e-297 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
  
 0.927
KWZ76675.1
Putative NAD-dependent malic enzyme; KEGG: apr:Apre_0229 3.6e-172 malate dehydrogenase K00027.
  
 
 0.856
Your Current Organism:
Anaerococcus tetradius
NCBI taxonomy Id: 33036
Other names: A. tetradius, ATCC 35098, CCM 3634, CCUG 17637, CCUG 46590, CIP 103927, DSM 2951, GIFU 7672, GIFU:7672, Gaffkya anaerobius, LMG 14264, LMG:14264, Peptostreptococcus tetradius, Tetracoccus anaerobius
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.