STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fhsKEGG: apr:Apre_1111 4.4e-254 Formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 7.50. (570 aa)    
Predicted Functional Partners:
purD
KEGG: apr:Apre_1107 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.67; Belongs to the GARS family.
  
 0.997
purH
KEGG: apr:Apre_1108 2.2e-234 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
 0.987
KWZ78968.1
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; KEGG: apr:Apre_1131 1.4e-81 tetrahydrofolate dehydrogenase/cyclohydrolase; K01491 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.979
purN
Putative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.972
KWZ78195.1
KEGG: apr:Apre_1626 1.2e-61 dihydrofolate reductase subunit; K00287 dihydrofolate reductase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.903
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.896
KWZ79182.1
Hypothetical protein; KEGG: ttm:Tthe_2240 8.5e-06 Methenyltetrahydrofolate cyclohydrolase; Psort location: Cytoplasmic, score: 7.50.
    
 0.890
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
  0.865
purC
KEGG: apr:Apre_1103 6.1e-106 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50; Belongs to the SAICAR synthetase family.
  
 
 0.826
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.816
Your Current Organism:
Anaerococcus tetradius
NCBI taxonomy Id: 33036
Other names: A. tetradius, ATCC 35098, CCM 3634, CCUG 17637, CCUG 46590, CIP 103927, DSM 2951, GIFU 7672, GIFU:7672, Gaffkya anaerobius, LMG 14264, LMG:14264, Peptostreptococcus tetradius, Tetracoccus anaerobius
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