STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ78515.1Preprotein translocase, SecE subunit; Psort location: CytoplasmicMembrane, score: 9.55; Belongs to the SecE/SEC61-gamma family. (60 aa)    
Predicted Functional Partners:
KWZ78936.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
 0.998
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 0.997
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
    
 0.993
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.990
rpmG
Ribosomal protein L33; KEGG: mmo:MMOB5490 3.8e-10 rpmG; 50S ribosomal protein L33 K02913; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL33 family.
  
 
 0.985
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.977
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
  
  
 0.976
rplW
Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
  
   0.967
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
 0.963
KWZ79191.1
Membrane protein insertase, YidC/Oxa1 family; Psort location: CytoplasmicMembrane, score: 10.00.
   
 0.960
Your Current Organism:
Anaerococcus tetradius
NCBI taxonomy Id: 33036
Other names: A. tetradius, ATCC 35098, CCM 3634, CCUG 17637, CCUG 46590, CIP 103927, DSM 2951, GIFU 7672, GIFU:7672, Gaffkya anaerobius, LMG 14264, LMG:14264, Peptostreptococcus tetradius, Tetracoccus anaerobius
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.