STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ78435.1DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (455 aa)    
Predicted Functional Partners:
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.821
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.810
KWZ78436.1
Putative glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
       0.773
KWZ78437.1
6-O-methylguanine DNA methyltransferase, DNA binding domain protein; KEGG: apr:Apre_0134 6.3e-40 methylated-DNA--protein-cysteine methyltransferase; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.652
KWZ78877.1
PIN domain protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.629
KWZ79428.1
KEGG: apr:Apre_1220 3.7e-225 DEAD/DEAH box helicase; K03724 ATP-dependent helicase Lhr and Lhr-like helicase; Psort location: Cytoplasmic, score: 7.50.
   
    0.617
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.602
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.591
KWZ79316.1
UvrD/REP helicase; ATP-dependent DNA helicase.
   
  
 0.556
KWZ77690.1
UvrD/REP helicase; KEGG: apr:Apre_1050 1.3e-231 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
   
  
 0.556
Your Current Organism:
Anaerococcus tetradius
NCBI taxonomy Id: 33036
Other names: A. tetradius, ATCC 35098, CCM 3634, CCUG 17637, CCUG 46590, CIP 103927, DSM 2951, GIFU 7672, GIFU:7672, Gaffkya anaerobius, LMG 14264, LMG:14264, Peptostreptococcus tetradius, Tetracoccus anaerobius
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