STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifSUnannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (395 aa)    
Predicted Functional Partners:
nifU
Unannotated protein.
 
 0.999
CDL18_03325
Unannotated protein.
  
 0.981
CDL24_09155
Unannotated protein.
 
  
 0.977
thiI
Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.959
CDL27_01120
Unannotated protein.
  
  
 
0.908
mnmA
Unannotated protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.905
selD
Unannotated protein; Synthesizes selenophosphate from selenide and ATP.
    
 0.894
yedF
Unannotated protein; Belongs to the sulfur carrier protein TusA family.
   
 
 0.869
CDL25_03520
Unannotated protein; Belongs to the PHP hydrolase family. HisK subfamily.
  
    0.735
dnaK
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
  
 0.567
Your Current Organism:
Ruminococcus gnavus
NCBI taxonomy Id: 33038
Other names: ATCC 29149, VPI C7-9, [. gnavus, [Ruminococcus] gnavus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.