STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALH79919.15-oxoprolinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1253 aa)    
Predicted Functional Partners:
ALH81425.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.932
ALH82328.1
Pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
  0.894
ALH81596.1
Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Start codon location was manually corrected by using GenomeMatcher.
    
 0.882
ALH82326.1
Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.880
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
    
  0.862
ALH81423.1
Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.861
ALH82118.1
Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.861
glsA
Glutaminase; Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family.
     
 0.820
nuoI
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
  0.802
ALH81409.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Start codon location was manually corrected by using GenomeMatcher.
   
 
 0.802
Your Current Organism:
Sphingopyxis macrogoltabida
NCBI taxonomy Id: 33050
Other names: ATCC 51380, CIP 104196, DSM 8826, IFO 15033, JCM 10192, LMG 17324, LMG:17324, NBRC 15033, S. macrogoltabida, Sphingomonas macrogolitabida, Sphingomonas macrogoltabidus, strain 203
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