Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_00515Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)    
Predicted Functional Partners:
SB4_00520
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.857
SB4_00525
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.857
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.857
SB4_00545
Nitrogen-fixing protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.762
mazG
Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
SB4_00535
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.618
SB4_00540
Sodium:proton exchanger; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.618
SB4_00550
Colicin V production protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.618
SB4_01640
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.471
SB4_01635
Peptidase S11; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
       0.467
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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