Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_01065Polyphenol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (255 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.932
mtnP
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
  0.921
SB4_05990
Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.916
SB4_12905
Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.916
SB4_05995
Molybdopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.915
SB4_06000
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.915
SB4_12895
Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.915
SB4_12900
Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.915
SB4_01075
ATP synthase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.912
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
    
 0.901
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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