Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
SB4_01225Chromosome partitioning protein ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (316 aa)    
Predicted Functional Partners:
SB4_12500
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
      0.888
SB4_05205
Sugar transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.882
SB4_01235
Membrane protease subunit HflC; HflC and HflK could regulate a protease.
 
 
   0.804
SB4_01230
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.764
SB4_01220
CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.742
SB4_01240
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
 
   
 0.739
SB4_00915
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.590
SB4_13640
Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.590
SB4_16560
Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.590
miaB
(dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
   
 0.577
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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