Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_03085Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (159 aa)    
Predicted Functional Partners:
SB4_10980
Glutathione reductase; Maintains high levels of reduced glutathione.
    
 0.957
SB4_12350
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.921
gshB
Glutathione synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
     
 0.906
SB4_02270
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.900
SB4_03135
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.900
SB4_03760
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.900
SB4_14535
Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
SB4_14675
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.900
SB4_15270
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.900
SB4_05700
Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.892
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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