Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_04020enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)    
Predicted Functional Partners:
SB4_12500
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.995
SB4_12520
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
fabZ
3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.981
SB4_12510
3-oxoacyl-ACP synthase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.934
SB4_12770
3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.926
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.925
SB4_13120
2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
SB4_08530
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.902
SB4_04010
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.869
SB4_04015
Ribonuclease BN; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.869
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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