Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SB4_04625Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 0.659
SB4_08950
Pyridoxal 4-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.596
SB4_12745
Hypothetical protein; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
   0.583
SB4_06265
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.573
SB4_18680
General secretion pathway protein GspA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.570
SB4_07770
NADP-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.557
SB4_14620
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.557
dinB-2
DNA repair protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.552
SB4_04635
2OG-Fe(II) oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.552
SB4_15975
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.543
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.