Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_05565Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
SB4_04225
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
SB4_05570
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.914
SB4_13015
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.909
SB4_03890
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.817
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.745
SB4_18215
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.699
SB4_18295
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.699
SB4_17990
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.695
SB4_11345
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.638
SB4_03875
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.607
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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