Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_08200Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)    
Predicted Functional Partners:
SB4_14875
CarD family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.765
SB4_08205
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.710
atpF-2
ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
     0.652
SB4_16755
GcrA cell cycle regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
lysK
lysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.607
SB4_14650
Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.594
SB4_10365
Cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.553
SB4_14665
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.546
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
    0.537
SB4_06885
N-formylglutamate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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