Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SB4_11340Opacity protein and related surface antigens-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)    
Predicted Functional Partners:
SB4_11345
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
       0.708
SB4_05925
Outer membrane family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.670
SB4_01030
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
SB4_13015
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.574
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.567
SB4_07360
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.556
SB4_06480
MltA-interacting MipA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.532
SB4_02750
ErfK/YbiS/YcfS/YnhG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.505
SB4_02955
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.489
SB4_09860
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.489
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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