STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SB4_11365Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.586
SB4_03915
Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.542
SB4_07595
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.539
SB4_15315
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.539
SB4_17345
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.535
SB4_04415
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
SB4_15900
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.513
SB4_04870
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
SB4_04885
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
SB4_07650
General secretion pathway protein GspL; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.501
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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