Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_120057, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)    
Predicted Functional Partners:
SB4_11390
Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
SB4_17890
Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.988
SB4_10690
Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.984
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
SB4_00630
Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
 
 
 0.934
SB4_03905
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.827
SB4_10710
Polynucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.787
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
  
 0.683
SB4_12000
uracil-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.659
SB4_08030
Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.655
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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